Pantoprazole Sodium Injection
Pantoprazole sodium for injection 40 mg (lyophilised injection).
Mechanism of action:
Pantoprazole is a proton pump inhibitor (ppi) that suppresses the final step in gastric acid production by covalently binding to the (h+, k+)-atpase enzyme system at the secretory surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The binding to the (h+, k+)-atpase results in a duration of antisecretory effect that persists longer than 24 hours for all doses tested.
Indications:
Pantoprazole is indicated for the treatment of gastric ulcer, duodenal ulcer, moderate and severe reflux oesophagitis.
