Product name: Scopolamine Hydrobromide
CAS NO: 114-49-8
About Scopolamine Hydrobromide:
Scopolamine Hydrobromide is an anticholine drug with the therapeutic effect as atropin. It is used clinically as drug for antegeneral anesthesia and for motion sickness, shaking palsy, manic psychosis and organophosphate poisoning.
Scopolamine hydrobromide is a competitive muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM.
Scopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed (Datura), angel's trumpets (Brugmansia), and corkwood (Duboisia). Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors, specifically M1 receptors; it is thus classified as an anticholinergic, antimuscarinic drug.
Its use in medicine is relatively limited, with its chief uses being in the treatment of motion sickness and postoperative nausea and vomiting. Scopolamine is named after the plant genus Scopolia. The name "hyoscine" is from the scientific name for henbane, Hyoscyamus niger.
