Autoantibody to Tsh Receptor (TRAb) Kit (Chemiluminescence Immunoassay)

Payment Terms: T/T,L/C,WU,Paypal
Trade on HiSupplier, Worry Free Guarantee
Trading safety, secure your money, lower the risk, protect both buyers and suppliers
HiSupplier is a Chinese multinational company in U.S, it helps to coordination and order landing.
More ›
  • Product Details
  • Company Profile
  • Product Reviews
Basic Info.
  • Brand Name: NORMAN 
  • Methodology: Chemiluminescence 
  • Service: International after-sales 
  • Specimen: serum 
  • Manufacturer: Independent R & D 
  • Type: Manufacturer 
  • Model No.: NRM-411 
  • Test time: 18 min 
  • Model No.: NRM-411 
  • Place of Origin: Jiangsu  
  • Min.Order: 1000 Piece/Pieces
  • Means of Transport: Ocean, Air, Land
Supply Capacity
  • Production Capacity: 1,000,000.00/Month
  • Packing:IN CARTON

Autoantibody To TSH Receptor (TRAb) Kit (Chemiluminescence Immunoassay)


Chemiluminescence Immunoassay

Product Show                                                                                                                                                                                                
Autoantibody to Tsh Receptor (TRAb) Kit (Chemiluminescence Immunoassay)


Autoantibody To TSH Receptor (TRAb) Kit (Chemiluminescence Immunoassay) is intended for in vitro quantitative determination of autoantibodies to TSH receptor  (TRAb) content in human serum, based on NRM411 system.
TRAb represents autoantibodies to the TSH receptor (or thyrotropin receptor), which is a receptor that responds to thyroid-stimulating hormone (TSH) and stimulates the production of thyroxine (T4) and triiodothyronine (T3). TRAb is closely related to Graves' disease and autoimmune hypothyroidism as it can activate TSH receptor stimulate the production of T4 and T3 as the same as TSH.

Clinical Significance                                                                                              

Clinically, TRAb content in human serum is an important index to diagnose Graves' disease and can be used to identify up to 80%~100% of the positive patients with Graves' disease. The presence of TRAb suggests that patients' hyperthyroidism is caused by autoimmune thyroid disease rather than toxic thyroid adenoma. TRAb may also present in patients with hypothyroidism and autoimmune thyroiditis thus TRAb test can also help with the diagnosis of these diseases.

Test Principle                                                                                                          

The assay is a sandwich immunoassay for quantitative determination of TRAb concentration based on chemiluminescence immunoassay technology. The Magnetic Microbeads Reagent contains protecting reagents and magnetic microbeads that are coated with biotin labeled TSHR antigen. The Antibody Reagent contains the protecting reagents and acridinium ester labeled goat anti-human IgG antibody. Auxiliary Reagent contains protecting reagents. Sample, calibrator or control is mixed with Magnetic Microbeads Reagent, Antibody Reagent and Auxiliary Reagent to form a sandwich complex. After incubation and automatic magnetic separation conducted by the instrument, trigger solutions are added to generate chemiluminescent reaction and the relative light units (RLUs) are measured by a photomultiplier. A proportional relationship presents between the concentration of TRAb in the sample and the RLUs detected by the NRM411 system.


100 Tests/Box, 200 Tests/Box.

Storage and Stability                                                                                            

Sealed: Stable until the expiry date when stored at 2-8ºC.
Opened: Stable for 4 weeks for reagents. Stable for 1 week after dissolved for the control material. To ensure the kit's best performance, it is recommended to place opened kits in the refrigerator if it's not going to be used on board during the next 12 hours.
Do not use it beyond the expiration date.

Calibration and Traceability                                                                                 

Each batch of kits contains specific calibration information, stored in the Calibration Card.
The TRAb assay is traceable to a NIBSC standard reference reagent (NIBSC code: 08/204).

Send message to this supplier
Ms. Ying Qin (Department Manager)
Tel: 86-25-58602219
Mobile: 13814717578
Enter between 20 to 3,000 chatacters.
Contact Method
Nanjing Norman Biological Technology Co., Ltd
No. 197 Pharmaceutical Valley Road, Jiangbei New Area, Nanjing, Jiangsu, China (Mainland) / 210000
Didn't find what you're looking for? Post Buying Lead or contact our customer service specialist for help!
Buyer Help Center