Anabolic Steroid Tamoxifen for Anti Cancer / Nolvadex Powder for Anti Estrogen CAS 10540-29-1

Price: 700.0 USD
Trade Term: FOB,CFR,CIF,DAT,FAS,DDP,DAP,CIP,CPT,FCA,EXW,DDU
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Basic Info.
  • Usage: bodybuilding 
  • Apprarance: White fine powder 
  • Alias: Steroids 
  • Model No.: CAS: 54965-24-1 
  • Place of Origin: Guangdong  
  • Min.Order: 3 Gram
  • Means of Transport: Express, Ocean, Air, Land
Supply Capacity
  • Production Capacity: Mass in stock
  • Packing:disguised
  • Delivery Date: 4~7days

Anabolic Steroid Tamoxifen for Anti Cancer / Nolvadex Powder for Anti Estrogen CAS 10540-29-1

 

Description:

 

This product is most often referred to as "Nolvadex" by bodybuilders. Nolvadex is not a steroid, rather a selective estrogen blocker. While Nolvadex doesn't prevent the buildup of estrogen in the body, it does prevent it from acting on certain receptors, most notably, those located in the nipples. This has obvious benefits to bodybuilders, because this is the area in which "gyno" occurs during the use of aromatizing steroids such as test .

 

Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.


The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroid were not studied though) from use of Nolvadex.
Thus, Dan Duchaine reported that it reduces IGF-1 and therefore reduces gains. However, if this effect exists at all, it must be very minor, due to the excellent gains that many have made, and from the fact that no one has noticed any such thing from Clomid, which has the same activity profile.
The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less, since weight gain is less, thus reinforcing the bias.

 

Product Specification:


Tamoxifen citrate/Nolvadex
Alias: Nolvadex;TAM
Trade names: Nolvadex, Istubal, Valodex, Genox
Chemical structure:
(Z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
1-p-beta-dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
CAS: 54965-24-1
Einecs No: 234-118-0
MF: C32H37NO8
MW: 563.64
Appearance:white to off-white powder
MP:140-144 ¡ãC
Storage temp.:2-8¡ãC
Water Solubility:slightly soluble
Usage: Tamoxifen citrate, a non-steroidal antiestrogen for oral administration, is commonly by athletes as a post cycle therapy drug to reduce or prevent the formation of excess estrogens that can lead to oily skin, acne, fluid retention, and gynecomastia.

2D Structure:

                                             

Purity: 99.3%~99.8%

 

COA:

Product name

Tamoxifen (Nolvadex)

Appearance

White crystalline powder

Identification

IR , UV conform

Conform

Loss on drying

¡Ü0.5ml

0.21ml

Residue on ignition

Not more than 0.2%

0.07ml

Iron

Not more than 0.005%

0.0017%

Heavy metals

Not more than 0.001%

0.0006%

Related substances

Total: Not more than 1.0% Individual: Not more than   0.5%

0.35% 0.13%

E-isomer

Not more than 0.3%

0.18%

Organic volatile impurities

Conforms

Conforms

Assay

99.0~101.0%

99.6%

 

Application :

 

1. Tamoxifen is highly effective in lowering the risk of breast cancer recurrence. In women who have already had breast cancer, tamoxifen also lowers the risk of breast cancer in the opposite breast (contralateral).Tamoxifen is used to prevent and treat breast cancers that test positive for estrogen receptors (ER+). It blocks the effects that the hormone estrogen has on cancer cells and lowers the chance that breast cancer will grow. It is often called an "anti-estrogen."For postmenopausal women, a two-stage treatment using tamoxifen and then an aromatase inhibitor, such as Arimidex, Aromasin, or Femara may work better than only taking tamoxifen.

 

2. Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy.

 

3. Belongs to a class of synthetic agents known as selective estrogen receptor modulators (SERMs). By competing with naturally occurring estrogen for binding sites on tissue cells, tamoxifen inhibits the stimulante effect of estrogen on breast cancers. Tumors that have been shown by biochemical assay to be rich in estrogen receptors are most likely to respond to treatment.

 

4. The drug has been found effective in reducing the risk of cancer recurrence or disease progression in women with or without axillary node metastasis. In women with extensive disease, tamoxifen therapy has been as effective as oophorectomy in retarding progression.

 

Effects of Tamoxifen Citrate :


For the anabolic steroid user the positive effects of Tamoxifen Citrate can be seen both during and post anabolic steroid use with post use being primary. Anabolic steroid like Test and Nandrolone among others will increase the body's serum estrogen levels. This occurs by the test  hormone converting to test , which happens due to it being metabolized by the aromatase enzyme. Once aromatized you have more estrogen, and this can lead to gynecomastia and water retention. It can also lead to high blood pressure if water retention becomes severe. Tamoxifen Citrate does not lower serum estrogen levels, but it will bind to the receptors in the chest preventing the estrogen from binding. It will not do a lot for water retention if that is an issue. It is also not enough gynecomastia protection for all men, but that depends on how high estrogen levels go as well as genetics. If more or stronger protection is needed Aromatase Inhibitors (AI's) are recommended. AI's are anti-estrogens that inhibit aromatase activity and lower serum estrogen levels.

We then have the test stimulateing effects of Tamoxifen Citrate. This is by far the most important effect for the anabolic steroid user. When we use anabolic steroid we suppress our natural test production, and this will occur regardless of the steroids used. Steroid use creates a negative feedback and tells your pituitary to stop making LH and FSH. This is why almost all steroid cycles include exogenous test so that the negative feedback doesn't cause a low test level. Once steroid use is complete something is then needed to jump start test production. It will occur on its own, but it will be slow and Tamoxifen can both speed it up and make it more efficient. Tamoxifen Citrate is introduced, LH and FSH levels go up and as a result test is produced.

Important Note: PCT use that includes Tamoxifen Citrate or any SERM, for it to be successful this assumes no prior low test  condition existed. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) during use. If prior low levels existed Tamoxifen Citrate won't magically fix this. If severe damage was done to the HPTA you will not recover and may be in need of low test  treatment.

Important Note: Many steroid users believe that a good PCT brings about full recovery, but this is a false belief. A PCT that includes Tamoxifen Citrate will stimulate recovery, but it will not end it. It will still take several months for full recovery to occur, but it stands a much better chance with PCT than without.

For the breast cancer patient the effects of Tamoxifen Citrate are perhaps even more straightforward than they are for the anabolic steroid user. Estrogen attaches and feeds the cancer, but Tamoxifen Citrate prevents it from attaching and starves the cancer. This is a simple yet effective means of treatment. This is not the only drug used in treatment; commonly treatment will begin with an AI and then will be switched to a SERM like Tamoxifen Citrate. It is also sometimes used as a preventative measure in those that have a strong family history of breast cancer.

 

Competitive Advantage:


High quality products, efficient service, safe shipping method,Supplying OEM Service

Nolvadex Istubal Valodex Genox Tamoxifen citrate



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Shenzhen Bohui Bio-Technology Co.,LTD
No.2095,Bixin Road,Longgang Street,Longgang District, Shenzhen, Guangdong, China (Mainland) / 518116
Fax: 86-755-6285663
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