Anti Cancer Fat Burning Supplements Nolvadex Powder CAS 10540-29-1 Tamoxifen Citrate

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Basic Info.
  • Usage: bodybuilding 
  • Apprarance: White fine powder 
  • Alias: Steroids 
  • skype: lisabesteroids 
  • Model No.: CAS: 54965-24-1 
  • Place of Origin: Guangdong  
  • Min.Order: 3 Gram
  • Means of Transport: Express, Ocean, Air, Land
Supply Capacity
  • Production Capacity: Mass in stock
  • Packing:disguised
  • Delivery Date: 4~7days

Anti Cancer Fat Burning Supplements Nolvadex Powder CAS 10540-29-1 Tamoxifen Citrate

 

What is Nolvadex?

 

Nolvadex, or Tamoxifen Citrate is a prescription drug that is used to treat breast cancer in both men and women. It can also be used as a preventive measure for women more likely to develop breast cancer due to age, genetics, or other high risk factors.

Tamoxifen (Nolva) is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine (anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.

Some breast cancer cells can require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. As a result, breast cancer cell growth is blocked.

Tamoxifen was discovered by pharmaceutical company Imperial Chemical Industries (now AstraZeneca) and is sold under the trade names Nolvadex, Istubal, and Valodex. However, the drug, even before its patent expiration, was and still is widely referred to by its generic name "tamoxifen."

 

Description:

 

Tamoxifen Citrate is a Selective Estrogen Receptor Modulator (SERM) that was created in 1961 by ICI now known as AstraZenaca. There are numerous brands including generic forms of Tamoxifen Citrate on the market, but Nolvadex is the most well known. Often referred to as an anti-estrogen, Tamoxifen Citrate is actually both an antagonist and agonist. This means it will act as an anti-estrogen in certain areas of the body while acting as an estrogen in other areas.

Tamoxifen Citrate has been used medically for decades and has been highly successful in breast cancer treatment, specifically hormone-responsive breast cancer. It is also a medication that is used by many anabolic steroid users, but it is not a steroid. This is a drug steroid users will sometimes use during steroid use to help with estrogenic related side effects brought on by specific steroids. However, it is most commonly used during Post Cycle Therapy (PCT). PCT is the 3-6 week period following steroid use that is implemented in order to help with natural test production that is suppressed during anabolic steroid use.

 

Product Specification:

 

Tamoxifen citrate/Nolvadex

Alias: Nolvadex;TAM
Trade names: Nolvadex, Istubal, Valodex, Genox
CAS: 54965-24-1

Einecs No: 234-118-0
MF: C32H37NO8
MW: 563.64
Appearance:white to off-white powder
Usage: Tamoxifen citrate, a non-steroidal antiestrogen for oral administration, is commonly by athletes as a post cycle therapy drug to reduce or prevent the formation of excess estrogens that can lead to oily skin, acne, fluid retention, and gynecomastia.

 

2D Structure:

                                             

Purity: 99%MIN.

COA:

Product name

Tamoxifen (Nolvadex)

Appearance

White crystalline powder

Identification

IR , UV conform

Conform

Loss on drying

¡Ü0.5ml

0.21ml

Residue on ignition

Not more than 0.2%

0.07ml

Iron

Not more than 0.005%

0.0017%

Heavy metals

Not more than 0.001%

0.0006%

Related substances

Total: Not more than 1.0% Individual: Not more than   0.5%

0.35% 0.13%

E-isomer

Not more than 0.3%

0.18%

Organic volatile impurities

Conforms

Conforms

Assay

99.0~101.0%

99.6%

 

Application:

 

Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a Selective estrogen-receptor modulator. Tamoxifen is the usual endocrine (anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.

 

Tamoxifen is used to treat infertility in women with anovulatory disorders. A dose of 10-40 mg per day is administered in days 3-7 of a woman's cycle.In addition, a rare condition occasionally treated with tamoxifen is retroperitoneal fibrosis. Tamoxifen is currently used for the treatment of both early and advanced ER+ (estrogen receptor positive) breast cancer in pre- and post-menopausal women. Additionally, it is the most common hormone treatment for male breast cancer.It is also approved by the FDA for the prevention of breast cancer in women at high risk of developing the disease.It has been further approved for the reduction of contralateral (in the opposite breast) cancer.

 

Tamoxifen also increase the risk of adverse side effects. Some cases of lower-limb lymphedema have been associated with the use of tamoxifen, due to the blood clots and deep vein thrombosis (DVT) that can be caused by this medication. Resolution of the blood clots or DVT is needed before lymphedema treatment can be initiated.

 

Tamoxifen Citrate Benefits:

 

For the anabolic steroid user the positive effects of Tamoxifen Citrate can be seen both during and post anabolic steroid use with post use being primary. Anabolic steroid like Test and Nandrolone among others will increase the body's serum estrogen levels. This occurs by the test hormone converting to

test , which happens due to it being metabolized by the aromatase enzyme. Once aromatized you have more estrogen, and this can lead to gynecomastia and water retention. It can also lead to high blood pressure if water retention becomes severe. Tamoxifen Citrate does not lower serum estrogen levels, but it will bind to the receptors in the chest preventing the estrogen from binding. It will not do a lot for water retention if that is an issue. It is also not enough gynecomastia protection for all men, but that depends on how high estrogen levels go as well as genetics. If more or stronger protection is needed Aromatase Inhibitors (AI's) are recommended. AI's are anti-estrogens that inhibit aromatase activity and lower serum estrogen levels.

We then have the test stimulating effects of Tamoxifen Citrate. This is by far the most important effect for the anabolic steroid user. When we use anabolic steroid we suppress our natural test production, and this will occur regardless of the steroids used. Steroid use creates a negative feedback and tells your pituitary to stop making LH and FSH. This is why almost all steroid cycles include exogenous test so that the negative feedback doesn't cause a low test level. Once steroid use is complete something is then needed to jump start test production. It will occur on its own, but it will be slow and Tamoxifen can both speed it up and make it more efficient. Tamoxifen Citrate is introduced, LH and FSH levels go up and as a result test is produced.

Important Note: PCT use that includes Tamoxifen Citrate or any SERM, for it to be successful this assumes no prior low test condition existed. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) during use. If prior low levels existed Tamoxifen Citrate won't magically fix this. If severe damage was done to the HPTA you will not recover and may be in need of low test treatment.

Important Note: Many steroid users believe that a good PCT brings about full recovery, but this is a false belief. A PCT that includes Tamoxifen Citrate will stimulate recovery, but it will not end it. It will still take several months for full recovery to occur, but it stands a much better chance with PCT than without.

For the breast cancer patient the effects of Tamoxifen Citrate are perhaps even more straightforward than they are for the anabolic steroid user. Estrogen attaches and feeds the cancer, but Tamoxifen Citrate prevents it from attaching and starves the cancer. This is a simple yet effective means of treatment. This is not the only drug used in treatment; commonly treatment will begin with an AI and then will be switched to a SERM like Tamoxifen Citrate. It is also sometimes used as a preventative measure in those that have a strong family history of breast cancer.

 

Side Effects of Tamoxifen Citrate


Possible side effects of Tamoxifen Citrate do exist, but it is one of the more well-tolerated SERM's on the market. Most men will not have an issue with this medication, although it is possible. Side effects of Tamoxifen Citrate do appear to be more common in women, but they are still not what we'd call "common." The most common side effects of Tamoxifen Citrate include:

¡¤ Vaginal Itching, bleeding, discharge or discomfort

Hot Flashes
Upset Stomach
Headaches
The above side effects of Tamoxifen Citrate are not extremely common but possible. Other possible side effects of the SERM's use but less common than the above include:

Rash
Decreased White Blood Cell Count
Endometrial Changes
Increased Triglyceride Levels
Pulmonary Embolism
Important Note: Women who are pregnant or who may become pregnant should not use Tamoxifen Citrate or any SERM as use will potentially damage the developing child and with strong probability.

 

Tamoxifen Citrate / Nolvadex 20mg/Ml Conversion Recipes:


Nolvadex Oral Conversion Recipes
50ml @ 20 mg/ml
1 gram of Tamoxifen Citrate
1 beaker suitable for holding the volume of liquids
19.6 ml of Glycerol
29.4 ml of 190 Proof Grain Alcohol

 

Professional Manufacture: We are genuine and legit pharmaceutical manufacturer, all products are produced under GMP conditions according to Standard Operation Procedure(SOP), not from little underground labs or black markets, so the quality is guaranteed.


Competitive Advantage:


High quality products, efficient service, safe shipping method,Supplying OEM Service

Injectable Tamoxifen citrate Nolvadex TAM Nolvadex Istubal Valodex Genox

 

 



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Shenzhen Bohui Bio-Technology Co.,LTD
No.2095,Bixin Road,Longgang Street,Longgang District, Shenzhen, Guangdong, China (Mainland) / 518116
Fax: 86-755-6285663
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