2-Deoxyglucose is a rare and natural monosaccharide that can be made from D-glucose, D-aminoglucose and some amino-polysaccharides. 2-DG exhibits various physiological and pharmacological effects on antivirus, anti-cancer and anti-aging. It has great potential in medicine, foods, and cosmetics.
Key Words: 2-DG
Preparation
Therapeutic effect
Application
2-Deoxyglucose (2-DG) is also called 2-deoxy-D-glucose, 2-deoxy-D-arabino-hexose or D-arabino-2-deoxyhexose. It is the basic structure of the anticancer drugs such as daunomycin, adriamycin, carminomycins and antibiotics with lactonic ring.
2-Deoxyglucose, 2-deoxy-glucose, 2dg glucose, 2-deoxy-d-glucose, 2DG has many functions, among them:
1. anti cancer - several US companies are undergoing clinical trials with 2DG for treating cancer.
2. weight loss - its unique property makes it an ideal weight loss management product.
3. Anti - aging - Scientific American once had a long article about the trial with 2DG.
4. Anti - Herpes - and treatment of aids
2-DG is an anti-metabolic glucose. It is also a rare and natural antibiotic mannose. It was first prepared from D-glucose in 1922. From then on, many scientists around the world have been studied from various prospects on the preparation process and physiological and pharmacological effects. It was found 2-DG can prohibit the growth of virus, bacteria and cancer cells. It also reduce the frequency of epilepsy, reduce its mortal rate, but also limit glucose metabolism in muscle, reducing energy creation, enlengthen life span. Therefore it has wide promising future in pharmaceutical, nutraceutical and cosmetic industries.
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