Miconazole Nitrate Cream 2% 30gm Antifungal Aluminium tube 1 TUBE / BOX
MICONAZOLE NITRATE CREAM 2% 30gm
COMPOSITION:
Each tube 30gm contains:Miconazole Nitrate 600MG
PHARMACOLOGICAL ACTION:
Miconazole nitrate is a synthetic 1- phenethylimidazole derivative. In vitro, low concentrations of miconazole
nitrate are fungistatic against all Phycomycetes, Ascomycetes and Adelomycetes tested and fungicidal against
Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum. Trichophyton interdigitale
and Microsporum canis.
It is a broad-spectrum anti-fungal agent. Miconazole nitrate also possesses some anti- bacterial activity against Gram- positive organisms.
In addition this cream has a very rapid alleviating effect on the pruritis which frequently accompanies infection.
INDICATIONS:
Dermatomycoses, e.g.:
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–Tinea pedis (Athlete's foot) |
Tinea cruris due to:
– Trichophyton mentagrophytes
– Trichophyton rubrum
– Microsporum audouinii
– Epidermophyton floccosumCandidial infections:
Infections of the skin (e.g. intertrigo)
Perianal infections
Stomatitis angularis (cheilitis, perlèche)
Balanoposthitis
CONTRA-INDICATIONS:
Miconazole Nitrate Cream is contra-indicated in those patients who have shown hypersensitivity to
miconazole.
DOSAGE AND DIRECTIONS FOR USE:
For external use only.
Miconazole Nitrate Cream should be applied to the lesions twice daily and thoroughly rubbed into the skin.
When all lesions have disappeared (usually after 2 to 5 weeks), treatment should be continued for a further
10 to 14 days to prevent relapse.
SIDE EFFECTS AND SPECIAL PRECAUTIONS:
Miconazole Nitrate Cream is excellently tolerated and leaves no stain on skin or clothes. Minimal absorption
of the active ingredient takes place through the skin and systemic side-effects are therefore most unlikely
to arise.Local irritation and sensitivity reactions may occur with DAKTARIN cream.
Drug interaction
Systemic absorption of miconazole, although low after topical administration, may potentiate the activity of
warfarin.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Poisoning or overdosage is unlikely to occur owing to the limited extent to which miconazole nitrate is
absorbed. If it does occur treatment should be along conventional lines.
STORAGE INSTRUCTIONS:
Store in a cool and dry place between 15-30°C . Protect from light.
KEEP OUT OF REACH OF CHILDREN.
